SKU: CB1096

HEK293 TSLPR/IL-7R STAT5-Luc

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£3,000.00
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£3,000.00
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A HEK293 cell line co-expressing TSLPR, IL-7RA and STAT5A, with a STAT5 RE luciferase reporter. Designed to monitor STAT5 signalling in response to receptor activation.

FOR RESEARCH USE ONLY

RoukenCells product packaging on a pink patterned background
  • RoukenCells product packaging on a pink patterned background
RoukenCells product packaging on a pink patterned background
Specification
Target/Receptor
TSLPR
IL-7RA
STAT5A
Aliases
CRLF2, Thymic stromal lymphopoietin protein receptor
CD127, IL-7 receptor subunit alpha
Signal transducer and activator of transcription 5A
Uniprot ID
Q13478
Q9HC73
P42229
Receptor Species
Homo sapiens
Homo sapiens
Homo sapiens
Response Element
STAT5
Reporter
Firefly Luciferase
Cell Line Background
HEK293
Target Information and Further Details
This HEK293 cell line expresses human thymic stromal lymphopoietin protein receptor (TSLPR, consisting of CRLF2 and IL-7 receptor subunit alpha), along with STAT5A and a STAT5 response element driving a luciferase reporter. It can be used to study TSLP signalling through STAT5 activation. TSLPR and IL-7R expression have been quantitatively assessed through flow cyometry and the cell line has been functionally validated for reporter signal in response to TSLP.
Performance Data

* Cells were then stained with a labelled antibody and expression levels quantified using a bead-based quantification kit. Specific induction conditions should be further defined by the user. Cell line suitable for preclinical research and development use only.

Shipping Details

Supplied as 1 vial of >3 million viable cells.

Specification Sheet

Access detailed product specifications, user guides and technical documentation in PDF format.

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