CB1503

CHO-K1 IndTROP2

£5,000.00
£5,000.00
Tax included.
In Stock

CHO-K1 IndTROP2 is an IndEx-2 stable cell line inducibly expressing full length human TROP2

FOR RESEARCH USE ONLY

Rouken Cells product packaging on a white background
  • Rouken Cells product packaging on a white background
Rouken Cells product packaging on a white background
Specification
Inducible Receptor
TROP2
CD Designation
TROP2
Gene name
TACSTD2
Aliases
TROP2, TACSTD2, GA733-1, EGP-1
Uniprot ID
P09758
Receptor Species
Homo sapiens
Cell Line Background
CHO-K1
Target Information and Further Details
TROP2 is a transmembrane glycoprotein encoded by the TACSTD2 gene, involved in calcium signalling, cell proliferation, and survival. It is overexpressed in a variety of epithelial cancers, including triple-negative breast cancer (TNBC), NSCLC, pancreatic, and colorectal cancers, and its expression often correlates with tumour aggressiveness and poor prognosis. TROP2 is the target of several ADCs, most notably sacituzumab govitecan, which is approved for TNBC and has shown activity in other solid tumours. Its cell surface accessibility and tumour specificity make it a promising therapeutic target.
Performance Data

Figure 1 – Histograms of TROP2 Induction at 0-100 µM Inducer.

Figure 2 – Quantification of TROP2 Induction at 0-100 µM Inducer.

* Cells were then stained with a labelled antibody and expression levels quantified using a bead-based quantification kit. Specific induction conditions should be further defined by the user. Cell line suitable for preclinical research and development use only.

Shipping Details

Supplied as 1 vial of >3 million viable cells.

* Please note that US import permits for CHO-K1 cell products are the responsibility of the US-based recipient/importer. RoukenCells is happy to provide supporting documentation (e.g. product descriptions and noninfectious statements) to assist with the import process.

Cell Line Datasheet

Access detailed product specifications, user guides and technical documentation in PDF format.

Download PDF

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