SKU: CB1567

CHO-K1 IndPSMA

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£5,000.00
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£5,000.00
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CHO-K1 IndPSMA is an IndEx-2 stable cell line inducibly expressing full length human PSMA.

FOR RESEARCH USE ONLY

Rouken Cells product packaging on a white background
  • Rouken Cells product packaging on a white background
Rouken Cells product packaging on a white background
Specification
Inducible Receptor
PSMA
CD Designation
PSMA
Gene name
FOLH1
Aliases
PSMA, FOLH1, GCPII
Uniprot ID
Q04609
Receptor Species
Homo sapiens
Cell Line Background
CHO-K1
Target Information and Further Details
PSMA is a type II transmembrane glycoprotein encoded by the FOLH1 gene (also known as glutamate carboxypeptidase II). It is highly expressed in prostate cancer cells, especially in metastatic and castration-resistant prostate cancer, while showing limited expression in normal tissues. PSMA is a prominent target for both diagnostic imaging (e.g., ^68Ga-PSMA PET) and therapeutic strategies such as radioligand therapy (^177Lu-PSMA-617). It is also under investigation as a target for ADCs and CAR-T therapies, reflecting its tumour-specific expression and clinical utility.
Performance Data

Figure 1 – Histograms of PSMA Induction at 0-100 µM Inducer.

Figure 2 – Quantification of PSMA Induction at 0-100 µM Inducer.

* Cells were then stained with a labelled antibody and expression levels quantified using a bead-based quantification kit. Specific induction conditions should be further defined by the user. Cell line suitable for preclinical research and development use only.

Shipping Details

Supplied as 1 vial of >3 million viable cells.

* Please note that US import permits for CHO-K1 cell products are the responsibility of the US-based recipient/importer. RoukenCells is happy to provide supporting documentation (e.g. product descriptions and noninfectious statements) to assist with the import process.

Cell Line Datasheet

Access detailed product specifications, user guides and technical documentation in PDF format.

Download PDF

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