CB1500

CHO-K1 IndCD19

£5,000.00
£5,000.00
Tax included.
In Stock

CHO-K1 IndCD19 is an IndEx-2 stable cell line inducibly expressing full length human CD19.

FOR RESEARCH USE ONLY

Vial labeled 'Rouken Cells' with technical specifications on a white background
Flow cytometry plot showing CD19 expression with induced and non-induced conditions.
  • Vial labeled 'Rouken Cells' with technical specifications on a white background
  • Flow cytometry plot showing CD19 expression with induced and non-induced conditions.
Vial labeled 'Rouken Cells' with technical specifications on a white background
Flow cytometry plot showing CD19 expression with induced and non-induced conditions.
Specification
Inducible Receptor
CD19
CD Designation
CD19
Gene name
CD19
Aliases
CD19, B-lymphocyte antigen CD19
Uniprot ID
P15391
Receptor Species
Homo sapiens
Cell Line Background
CHO-K1
Target Information and Further Details
CD19 is a transmembrane glycoprotein expressed on the surface of B cells throughout most stages of their development and is encoded by the CD19 gene. It functions as a co-receptor in the B-cell receptor (BCR) complex, enhancing signalling and modulating B-cell activation. CD19 is highly expressed in most B-cell malignancies, including acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma (NHL). Due to its broad and consistent expression in B-cell cancers, it is a major target in immunotherapies such as CAR-T cell therapy (e.g., tisagenlecleucel) and bispecific T-cell engagers (e.g., blinatumomab).
Performance Data
Flow cytometry plot showing CD19 expression with induced and non-induced conditions.

Figure 1 – Histograms of CD19 Induction at 0-100 µM Inducer+Q3:AC3.

Figure 2 – Quantification of CD19 Induction at 0-100 µM Inducer.

* Cells were then stained with a labelled antibody and expression levels quantified using a bead-based quantification kit. Specific induction conditions should be further defined by the user. Cell line suitable for preclinical research and development use only.

Shipping Details

Supplied as 1 vial of >3 million viable cells.

* Please note that US import permits for CHO-K1 cell products are the responsibility of the US-based recipient/importer. RoukenCells is happy to provide supporting documentation (e.g. product descriptions and noninfectious statements) to assist with the import process.

Cell Line Datasheet

Access detailed product specifications, user guides and technical documentation in PDF format.

Download PDF

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